Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

8-Hydroxyquinoline derivative as a fluorescent chemosensor for zinc ion.

8-Hydroxyquinoline derivative 1 as a fluorescent chemosensor for Zn2+ was synthesized. Because Cd2+ is often found with Zn2+ in the environment and can form fluorescent complexes with chelating fluorophores, a potentially important property of chemosensors for Zn2+ is their selectivity for Zn2+ over Cd2+. The Zn2+ or Cd2+ complexes of 1 gave an emission band from the 1:1 complex, but the fluore...

متن کامل

Bright, red emitting fluorescent sensor for intracellular imaging of Mg2+ .

Fluorescent sensors with low-energy excitation are in great demand for the study of cellular Mg2+ by fluorescence miscroscopy, but to date they remain scarce. Addressing this gap, we report herein a new set of molecular fluorescent sensors for the detection of Mg2+ based on an o-aminophenol-N,N,O-triacetic acid (APTRA) metal-recognition moiety combined with two different BODIPY fluorophores. Th...

متن کامل

Bright fluorescent nanoparticles for developing potential optical imaging contrast agents.

Fluorescent cross-linked nanoparticles with variable fluorophore loading amounts, locations, and particle sizes were synthesized from sequential one-pot functionalization/cross-linking of block copolymer micelles with amine-terminated dye and cross-linker molecules, via reductive amination and amidation. The fluorescence quantum yield and brightness of these nanoparticles were evaluated by stea...

متن کامل

A highly selective fluorescent chemosensor for Pb2+.

A new fluorescent sensor based on rhodamine B for Pb2+ was synthesized. The new fluorescent sensor showed an extreme selectivity for Pb2+ over other metal ions examined in acetonitrile. Upon the addition of Pb2+, an overall emission change of 100-fold was observed, and the selectivity was calculated to be 200 times that of Zn2+. The signal transduction occurs via of reversible CHEF (chelation-e...

متن کامل

A Ratiometric Tetrazolylpyridine-Based “Turn-On” Fluorescent Chemosensor for Zinc(II) Ion in Aqueous Media

Zinc, an essential trace element, is the second most abundant metal in the human body that plays a vital role in numerous biological processes, such as peptide synthesis, DNA synthesis, RNA transcription, metabolism of cells, metalloenzyme regulation, and neurophysiology, and it also induces the formation of b-amyloid, which is related to neurological function. More than 100 enzymes, such as pe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Chemistry & Biology

سال: 2004

ISSN: 1074-5521

DOI: 10.1016/j.chembiol.2004.01.017